Effect of Lagenaria siceraria fruit extract (Bottle gourd) on hepatotoxicity induced by antitubercular drugs in albino rats

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منابع مشابه

Bottle Gourd (Lagenaria Siceraria) Juice Poisoning.

We present the case of a young woman who presented to us with multiple episodes of vomiting, followed by hematemesis and abdominal pain after consuming bottle gourd juice. The patient was resuscitated and stabilized with fluids, proton pump inhibitors and antiemetics and discharged in stable condition. As a member of the Cucurbitaceae family, bottle gourd contains toxic tetracyclic triterpenoid...

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Effect of Ocimum sanctum (OS) leaf extract on hepatotoxicity induced by antitubercular drugs in rats.

Healthy adult albino rats of either sex of Wistar strain weighing 150 to 250 g were used after approval of the Institutional Ethics Committee. They were kept on standard pellet diet and were allowed free access to food and water. The doses of antitubercular drugs (isoniazid (I)-27 mg/kg/day, rifampicin (R)-54 mg/kg/day, pyrazinamide (Z)-135 mg/kg/day) were extrapolated from daily human dose usi...

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Assessment of effects on health due to consumption of bitter bottle gourd (Lagenaria siceraria) juice

BACKGROUND & OBJECTIVES The bottle gourd (Lagenaria siceraria) is popularly known as lauki, ghia or dudhi in India. Its consumption is advocated by traditional healers for controlling diabetes mellitus, hypertension, liver diseases, weight loss and other associated benefits. However, in last few years there have been reports of suspected toxicity due to consumption of its juice. This led to the...

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Effect of Lagenaria siceraria fruit powder on sodium oxalate induced urolithiasis in Wistar rats

BACKGROUND In spite of advances in the present practice of medicine, the formation and growth of calculi continues to trouble mankind, as there is no satisfactory drug to treat kidney stones. In India, many indigenous drugs are in use for the treatment of urinary calculus disease. OBJECTIVE The present study was intended to determine anti-urolithiatic effect of Lagenaria siceraria fruit powde...

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ژورنال

عنوان ژورنال: International Journal of Basic & Clinical Pharmacology

سال: 2013

ISSN: 2319-2003

DOI: 10.5455/2319-2003.ijbcp20131211